1. What is HOMA-B?

HOMA-B (Homeostatic Model Assessment for Beta Cell Function) is a mathematical model that estimates beta cell function from fasting insulin and glucose levels. It provides an assessment of pancreatic beta cell function in the fasting state.

2. How Does the Calculator Work?

The calculator uses the HOMA-B formula:

Where:

• Fasting Insulin — Measured in μU/L
• Fasting Glucose — Measured in mmol/L

Explanation: The equation estimates beta cell function as a percentage of normal, with higher values indicating better beta cell function.

3. Importance of HOMA-B Calculation

Details: HOMA-B is widely used in research and clinical practice to assess insulin secretion capacity and beta cell function, particularly in diabetes research and metabolic studies.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be positive numbers, and glucose must be greater than 3.5 mmol/L for valid calculation.

5. Frequently Asked Questions (FAQ)

Q1: What are normal HOMA-B values?
A: Normal HOMA-B values typically range from 70-110% in healthy individuals, though this can vary based on age, BMI, and other factors.

Q2: How does HOMA-B differ from HOMA-IR?
A: HOMA-B assesses beta cell function (insulin secretion), while HOMA-IR assesses insulin resistance. Both are part of the HOMA model.

Q3: When should HOMA-B be measured?
A: HOMA-B should be calculated from fasting blood samples collected after an overnight fast of 8-12 hours.

Q4: Are there limitations to HOMA-B?
A: Yes, HOMA-B provides an estimate rather than direct measurement and may be less accurate in certain populations like those with very high or very low insulin levels.

Q5: Can HOMA-B be used for diagnosis?
A: HOMA-B is primarily used for research and assessment purposes rather than clinical diagnosis of diabetes.