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How to Calculate HOMA

HOMA-IR Formula:

\[ HOMA-IR = \frac{\text{Fasting Insulin} \times \text{Fasting Glucose}}{405} \]

μU/mL
mg/dL

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1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

\[ HOMA-IR = \frac{\text{Fasting Insulin} \times \text{Fasting Glucose}}{405} \]

Where:

Explanation: The equation provides a simple way to estimate insulin resistance using fasting blood measurements.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is widely used in research and clinical practice to assess insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest significant insulin resistance.

Q2: When should HOMA-IR testing be done?
A: Testing should be performed after an overnight fast of 8-12 hours for accurate results.

Q3: Are there limitations to HOMA-IR?
A: HOMA-IR provides an estimate rather than a direct measurement and may be less accurate in certain populations like pregnant women or those with liver disease.

Q4: Can HOMA-IR be used for diagnosis?
A: While useful for screening and research, HOMA-IR should not be used alone for clinical diagnosis without additional tests and clinical evaluation.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context, typically as part of metabolic health assessments.

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