1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It's calculated from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in μU/mL (microinternational units per milliliter)
• Fasting Glucose — Measured in mg/dL (milligrams per deciliter)
• 405 — The constant denominator in the formula

Explanation: The formula estimates insulin resistance by assessing the relationship between fasting glucose and insulin levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is a valuable tool for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity. Values between 1.0-2.0 suggest early insulin resistance, and values above 2.0 indicate significant insulin resistance.

Q2: When should I test for HOMA-IR?
A: Testing should be done after an 8-12 hour fast, preferably in the morning. Avoid testing after illness, stress, or changes in medication.

Q3: Are there limitations to HOMA-IR?
A: Yes, it's less accurate in people with impaired beta-cell function, type 1 diabetes, or those using medications that affect insulin secretion.

Q4: Can HOMA-IR be used for diagnosis?
A: HOMA-IR is a screening tool, not a diagnostic test. Clinical evaluation and additional tests are needed for definitive diagnosis of insulin resistance.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context. Typically, it's measured annually for at-risk individuals or when monitoring treatment response.