1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin resistance based on fasting insulin and glucose levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL
• 405 — Constant factor for unit conversion

Explanation: The formula calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is important for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular diseases. It helps in early detection and monitoring of insulin resistance.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0). The calculator will compute the HOMA-IR value.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, HOMA-IR values below 2.5 are considered normal, though this may vary by population and laboratory standards.

Q2: When should HOMA-IR be measured?
A: It should be measured after an overnight fast (8-12 hours) for accurate results.

Q3: Are there limitations to HOMA-IR?
A: Yes, it may not be as accurate in certain populations such as those with type 1 diabetes or extreme insulin resistance.

Q4: Can HOMA-IR be used for diagnosis?
A: While it's a useful screening tool, it should be used in conjunction with other clinical assessments for diagnosis.

Q5: How often should HOMA-IR be tested?
A: Frequency depends on individual risk factors and clinical context, typically as part of metabolic health assessments.