1. What is the HOMA-IR Equation?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) equation estimates insulin resistance using fasting insulin and glucose levels. It provides a simple method to assess insulin sensitivity and identify potential metabolic disorders.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL
• 405 — Constant factor for unit conversion

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels, with higher values indicating greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is crucial for identifying insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease risk assessment.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be obtained from laboratory tests after an overnight fast for accurate results.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 2.0 are considered normal, though this may vary by population and laboratory standards.

Q2: When should HOMA-IR be measured?
A: After an overnight fast (8-12 hours), preferably in the morning before any food or caloric intake.

Q3: Are there limitations to HOMA-IR?
A: HOMA-IR provides an estimate and may not be as accurate as more complex tests like hyperinsulinemic-euglycemic clamp.

Q4: Can HOMA-IR be used for diagnosis?
A: While useful for screening and research, clinical diagnosis should be based on comprehensive medical evaluation.

Q5: How often should HOMA-IR be checked?
A: Frequency depends on individual risk factors and should be determined by healthcare providers.