1. What is HOMA-B?

HOMA-B (Homeostatic Model Assessment for Beta Cell Function) is a mathematical model that estimates beta cell function from fasting glucose and insulin concentrations. It provides an assessment of pancreatic beta cell function in the fasting state.

2. How Does the Calculator Work?

The calculator uses the HOMA-B formula:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL

Explanation: The equation estimates beta cell function as a percentage of normal, with 100% representing normal function.

3. Importance of HOMA-B Calculation

Details: HOMA-B is valuable for assessing insulin secretion capacity, monitoring beta cell function in diabetes research, and evaluating insulin resistance syndromes.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be positive, and glucose must be greater than 63 mg/dL for valid calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-B value?
A: Normal HOMA-B values typically range between 70-110%, with 100% representing normal beta cell function.

Q2: How does HOMA-B relate to diabetes?
A: Lower HOMA-B values indicate impaired beta cell function, which is characteristic of type 2 diabetes progression.

Q3: When should HOMA-B be measured?
A: HOMA-B should be calculated from fasting blood samples collected after an overnight fast of 8-12 hours.

Q4: Are there limitations to HOMA-B?
A: HOMA-B provides an estimate rather than a direct measurement and may be less accurate in extreme glycemic conditions.

Q5: Can HOMA-B be used for clinical diagnosis?
A: While useful for research and monitoring, HOMA-B should not be used alone for clinical diagnosis without additional tests.