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HOMA-IR Calculator

HOMA-IR Formula:

\[ HOMA-IR = \frac{\text{Fasting Insulin} \times \text{Fasting Glucose}}{405} \]

μU/mL
mg/dL

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1. What Is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It's calculated from fasting blood glucose and insulin levels.

2. How Is HOMA Index Calculated

The calculator uses the HOMA-IR formula:

\[ HOMA-IR = \frac{\text{Fasting Insulin} \times \text{Fasting Glucose}}{405} \]

Where:

Explanation: The formula estimates insulin resistance based on the relationship between fasting glucose and insulin levels. Lower values indicate better insulin sensitivity, while higher values suggest insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is a valuable tool for assessing insulin resistance, which is associated with various metabolic disorders including type 2 diabetes, metabolic syndrome, and polycystic ovary syndrome (PCOS).

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, values between 1.0-1.9 suggest early insulin resistance, and values above 2.0 indicate significant insulin resistance.

Q2: When should I test for HOMA-IR?
A: Testing should be done after an overnight fast of 8-12 hours for accurate results.

Q3: Are there limitations to HOMA-IR?
A: While useful for population studies, HOMA-IR may not be as accurate for individuals with extreme insulin resistance or beta-cell dysfunction.

Q4: Can HOMA-IR diagnose diabetes?
A: HOMA-IR assesses insulin resistance but is not a diagnostic tool for diabetes. Formal glucose tolerance tests are needed for diabetes diagnosis.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context, typically every 6-12 months for those at risk of metabolic disorders.

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