HOMA-IR Formula:
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HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It's calculated from fasting blood glucose and insulin levels.
The calculator uses the HOMA-IR formula:
Where:
Explanation: The formula estimates insulin resistance based on the relationship between fasting glucose and insulin levels. Lower values indicate better insulin sensitivity, while higher values suggest insulin resistance.
Details: HOMA-IR is a valuable tool for assessing insulin resistance, which is associated with various metabolic disorders including type 2 diabetes, metabolic syndrome, and polycystic ovary syndrome (PCOS).
Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be greater than zero for accurate calculation.
Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, values between 1.0-1.9 suggest early insulin resistance, and values above 2.0 indicate significant insulin resistance.
Q2: When should I test for HOMA-IR?
A: Testing should be done after an overnight fast of 8-12 hours for accurate results.
Q3: Are there limitations to HOMA-IR?
A: While useful for population studies, HOMA-IR may not be as accurate for individuals with extreme insulin resistance or beta-cell dysfunction.
Q4: Can HOMA-IR diagnose diabetes?
A: HOMA-IR assesses insulin resistance but is not a diagnostic tool for diabetes. Formal glucose tolerance tests are needed for diabetes diagnosis.
Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context, typically every 6-12 months for those at risk of metabolic disorders.