1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin resistance from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL

Explanation: The formula calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels, with higher values indicating greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is widely used in clinical research and practice to assess insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid and greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Normal HOMA-IR values typically range from 1.0 to 1.5. Values above 2.0 may indicate insulin resistance.

Q2: When should HOMA-IR be measured?
A: HOMA-IR should be calculated from fasting blood samples collected after an overnight fast of 8-12 hours.

Q3: Are there limitations to HOMA-IR?
A: While useful for population studies, HOMA-IR may be less accurate in individuals with extreme insulin resistance or beta-cell dysfunction.

Q4: Can HOMA-IR be used for diagnosis?
A: HOMA-IR is primarily used as a research tool and screening method rather than a definitive diagnostic test for insulin resistance.

Q5: How does HOMA-IR compare to other insulin resistance measures?
A: HOMA-IR correlates well with more complex methods like the hyperinsulinemic-euglycemic clamp, though the clamp remains the gold standard.