1. What is the HOMA-IR Index?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides a simple way to assess insulin sensitivity from fasting glucose and insulin measurements.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels, with higher values indicating greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is widely used in clinical research and practice to identify insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 2.0 are considered normal, though this may vary by population and laboratory standards.

Q2: How does HOMA-IR relate to diabetes risk?
A: Higher HOMA-IR values indicate greater insulin resistance, which is a major risk factor for developing type 2 diabetes.

Q3: When should HOMA-IR be measured?
A: HOMA-IR should be calculated from fasting blood samples collected after an overnight fast for accurate results.

Q4: Are there limitations to HOMA-IR?
A: While useful for population studies, HOMA-IR may be less accurate in individuals with impaired glucose tolerance or diabetes.

Q5: Can HOMA-IR be used for clinical diagnosis?
A: HOMA-IR is primarily used as a research tool and screening method rather than a definitive diagnostic test for insulin resistance.