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HOMA-IR Formula:
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HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin resistance based on fasting insulin and glucose levels.
The calculator uses the HOMA-IR formula:
Where:
Explanation: The formula calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels, with higher values indicating greater insulin resistance.
Details: HOMA-IR is widely used in clinical research and practice to assess insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease risk.
Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0). For accurate results, measurements should be taken after an overnight fast.
Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest insulin resistance. However, reference ranges may vary.
Q2: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context. It's commonly used in research settings and for monitoring patients with metabolic disorders.
Q3: Are there limitations to HOMA-IR?
A: Yes, HOMA-IR provides an estimate rather than a direct measurement of insulin resistance and may be less accurate in certain populations or extreme conditions.
Q4: Can HOMA-IR be used for diagnosis?
A: While useful for assessing insulin resistance, HOMA-IR should be interpreted alongside other clinical findings and not used as a sole diagnostic tool.
Q5: What factors can affect HOMA-IR results?
A: Recent food intake, medications, stress, and timing of blood draw can all influence results. Fasting samples provide the most accurate assessment.