1. What is the HOMA-IR Index?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) index is a method used to quantify insulin resistance and beta-cell function. It provides a simple and reliable assessment of insulin sensitivity from fasting glucose and insulin measurements.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL

Explanation: The equation estimates insulin resistance by assessing the relationship between fasting insulin and glucose levels, with higher values indicating greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is crucial for identifying insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease risk assessment.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0). Morning fasting samples provide the most accurate results.

5. Frequently Asked Questions (FAQ)

Q1: What are normal HOMA-IR values?
A: Normal HOMA-IR values are typically below 2.5-3.0, though this may vary by population. Values above this range suggest insulin resistance.

Q2: How does HOMA-IR compare to other insulin resistance tests?
A: HOMA-IR is simpler and less expensive than glucose clamp techniques, though the latter is considered the gold standard for insulin resistance assessment.

Q3: When should insulin and glucose be measured?
A: Morning fasting samples are essential for accurate HOMA-IR calculation. Avoid testing after meals or during illness.

Q4: Are there limitations to the HOMA-IR calculation?
A: HOMA-IR may be less accurate in certain populations, such as those with type 1 diabetes, liver disease, or during pregnancy.

Q5: Can HOMA-IR be used for diagnosis?
A: While HOMA-IR is a useful screening tool, clinical diagnosis should be based on comprehensive assessment including medical history and additional tests.