1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides a simple way to assess insulin resistance using fasting glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• \( Fasting\ Insulin \) — Measured in μU/mL
• \( Fasting\ Glucose \) — Measured in mg/dL

Explanation: The formula calculates insulin resistance based on the product of fasting insulin and glucose levels, normalized by the constant 405.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is widely used in clinical research and practice to identify insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 2.0 are considered normal, while values above 2.5-3.0 indicate insulin resistance.

Q2: When should the test be performed?
A: Blood samples should be collected after an overnight fast (8-12 hours) for accurate results.

Q3: Are there limitations to HOMA-IR?
A: HOMA-IR provides an estimate and may not be as accurate as more complex tests like hyperinsulinemic-euglycemic clamp.

Q4: Can HOMA-IR be used for diagnosis?
A: While useful for screening and research, HOMA-IR should be interpreted alongside other clinical findings and not used alone for diagnosis.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context, typically as part of metabolic health assessments.