HOMA IR Calculator Pmol L

HOMA-IR Equation:

\[ HOMA-IR = \frac{(Fasting\ Insulin\ (pmol/L) / 6) \times Fasting\ Glucose\ (mmol/L)}{22.5} \]

HOMA-IR Score:

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1. What is the HOMA-IR Calculator?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) calculator estimates insulin resistance from fasting insulin and glucose levels. This model provides a simple and reliable method to assess insulin sensitivity in clinical practice.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

\[ HOMA-IR = \frac{(Fasting\ Insulin\ (pmol/L) / 6) \times Fasting\ Glucose\ (mmol/L)}{22.5} \]

Where:

\( Fasting\ Insulin \) — Serum insulin level in pmol/L
\( Fasting\ Glucose \) — Blood glucose level in mmol/L
6 — Conversion factor from pmol/L to μU/mL
22.5 — Normalization constant

Explanation: The equation converts insulin from pmol/L to μU/mL and calculates the product of insulin and glucose levels normalized to standard values.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is a valuable tool for identifying insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease risk assessment.

4. Using the Calculator

Tips: Enter fasting insulin in pmol/L and fasting glucose in mmol/L. Both values must be valid (greater than 0). Morning fasting samples provide the most accurate results.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 2.0 are considered normal, while values above 2.5 indicate insulin resistance. However, these thresholds may vary by population.

Q2: Why convert insulin from pmol/L?
A: The original HOMA-IR formula uses μU/mL for insulin. Since 1 μU/mL = 6 pmol/L, we divide by 6 for proper conversion.

Q3: When should insulin and glucose be measured?
A: Morning fasting samples after an 8-12 hour overnight fast provide the most reliable results for HOMA-IR calculation.

Q4: Are there limitations to HOMA-IR?
A: HOMA-IR may be less accurate in certain populations such as pregnant women, elderly individuals, and those with liver disease or extreme BMI values.

Q5: How often should HOMA-IR be measured?
A: For monitoring purposes, HOMA-IR can be measured every 3-6 months, or as recommended by your healthcare provider based on individual risk factors.