1. What is the HOMA-IR Equation?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) equation estimates insulin resistance using fasting insulin and glucose levels. It's commonly used in clinical practice and research to assess metabolic health.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• Fasting Insulin — Measured in μU/L (micro units per liter)
• Fasting Glucose — Measured in mmol/L (millimoles per liter)
• 22.5 — Normalization constant

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels, with higher values indicating greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is a valuable tool for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, cardiovascular disease, and other metabolic disorders.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be valid and greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What are normal HOMA-IR values?
A: Normal HOMA-IR values typically range from 1.0 to 1.5. Values above 2.0 suggest insulin resistance, and values above 2.5 indicate significant insulin resistance.

Q2: Why use mmol/L units for glucose?
A: mmol/L units are commonly used in India and many other countries outside the United States for glucose measurement.

Q3: When should insulin and glucose be measured?
A: Both should be measured after an 8-12 hour fasting period for accurate results.

Q4: Are there limitations to HOMA-IR?
A: HOMA-IR provides an estimate rather than a direct measurement of insulin resistance and may be less accurate in certain populations.

Q5: Can HOMA-IR be used for diagnosis?
A: While HOMA-IR is a useful screening tool, clinical diagnosis should be based on comprehensive assessment including other tests and clinical evaluation.