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HOMA-IR Equation:
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The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) equation estimates insulin resistance from fasting insulin and glucose levels. It provides a simple method to assess insulin sensitivity and identify individuals at risk for metabolic disorders.
The calculator uses the HOMA-IR equation:
Where:
Explanation: The equation calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels, with higher values indicating greater insulin resistance.
Details: HOMA-IR assessment is crucial for identifying insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease risk.
Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0). Morning fasting samples provide the most accurate results.
Q1: What are normal HOMA-IR values?
A: Normal HOMA-IR values are typically below 2.0, though this may vary by population. Values above 2.5 often indicate insulin resistance.
Q2: How does HOMA-IR compare to other insulin resistance tests?
A: HOMA-IR is a simple screening tool. More comprehensive tests like hyperinsulinemic-euglycemic clamps provide more accurate assessment but are more complex.
Q3: When should insulin and glucose be measured?
A: Morning fasting samples after an 8-12 hour fast provide the most reliable results for HOMA-IR calculation.
Q4: Are there limitations to the HOMA-IR equation?
A: HOMA-IR may be less accurate in individuals with impaired beta-cell function, type 1 diabetes, or those using certain medications affecting glucose metabolism.
Q5: Can HOMA-IR be used for diagnosis?
A: HOMA-IR is a screening tool and should be used in conjunction with other clinical assessments for diagnosis of insulin resistance and related conditions.