1. What is the HOMA-IR Calculation?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin sensitivity from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• \( Fasting\ Insulin \) — Measured in μU/mL
• \( Fasting\ Glucose \) — Measured in mg/dL

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting glucose and insulin levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is a valuable tool for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0).

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest significant insulin resistance.

Q2: When should I get tested for HOMA-IR?
A: Testing is recommended for individuals with risk factors for insulin resistance, such as obesity, family history of diabetes, or polycystic ovary syndrome.

Q3: How should I prepare for the test?
A: A 8-12 hour fast is required before blood collection for accurate fasting insulin and glucose measurements.

Q4: Are there limitations to HOMA-IR?
A: While useful for population studies, HOMA-IR may not be as accurate for individuals as more complex tests like the hyperinsulinemic-euglycemic clamp.

Q5: Can HOMA-IR diagnose diabetes?
A: HOMA-IR assesses insulin resistance but is not a diagnostic test for diabetes. Diagnosis requires specific glucose tolerance tests or HbA1c measurements.