Homa Calculator Oxford

HOMA2 Calculator:

Uses computational model from Oxford University to calculate HOMA2-IR, HOMA2-%B, and HOMA2-%S

HOMA2-IR:

HOMA2-%B:

HOMA2-%S:

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1. What is the HOMA Calculator Oxford?

The HOMA Calculator from Oxford University is a computational model that estimates insulin resistance (HOMA2-IR), beta-cell function (HOMA2-%B), and insulin sensitivity (HOMA2-%S) from fasting insulin and glucose measurements.

2. How Does the Calculator Work?

The calculator uses the sophisticated HOMA2 model developed by Oxford University:

Computational model (no simple algebraic formula) that solves differential equations describing glucose-insulin homeostasis

Input Parameters:

Fasting Insulin (μU/mL or pmol/L)
Fasting Glucose (mg/dL or mmol/L)

Output Values:

HOMA2-IR - Insulin resistance index
HOMA2-%B - Beta-cell function percentage
HOMA2-%S - Insulin sensitivity percentage

3. Importance of HOMA2 Calculation

Details: The HOMA2 model provides more accurate assessment of insulin resistance and beta-cell function compared to the original HOMA1 model, particularly across a wider range of glucose and insulin values.

4. Using the Calculator

Tips: Enter fasting insulin and glucose values with appropriate units. For optimal results, use morning fasting samples collected after an overnight fast.

5. Frequently Asked Questions (FAQ)

Q1: Why use HOMA2 instead of HOMA1?
A: HOMA2 provides more accurate results across a wider range of values and uses a computational model that better reflects human physiology.

Q2: What are normal HOMA2 values?
A: HOMA2-IR values below 1.0 indicate normal insulin sensitivity. Values above 1.9 suggest insulin resistance, and above 2.9 indicate significant insulin resistance.

Q3: When should insulin and glucose be measured?
A: Morning fasting samples after an 8-12 hour overnight fast provide the most reliable results.

Q4: Are there limitations to the HOMA2 model?
A: The model assumes steady-state conditions and may be less accurate in conditions of rapidly changing glucose or insulin levels.

Q5: How does this differ from the original HOMA calculator?
A: HOMA2 uses a more sophisticated computational model that provides separate estimates for insulin resistance, beta-cell function, and insulin sensitivity.