1. What is the HOMA-IR Calculation?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an assessment of insulin resistance from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• \( Fasting\ Insulin \) — Fasting insulin level (μU/mL)
• \( Fasting\ Glucose \) — Fasting glucose level (mg/dL)

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is important for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0).

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest insulin resistance.

Q2: When should HOMA-IR be measured?
A: HOMA-IR should be calculated from fasting blood samples taken after an overnight fast of 8-12 hours.

Q3: Are there limitations to HOMA-IR?
A: HOMA-IR is a simple estimate and may not be as accurate as more complex methods like hyperinsulinemic-euglycemic clamp.

Q4: Can HOMA-IR be used for diagnosis?
A: HOMA-IR is used as a screening tool and research measure, but clinical diagnosis should be based on comprehensive assessment.

Q5: How often should HOMA-IR be monitored?
A: Frequency depends on individual risk factors and clinical context, typically every 6-12 months for at-risk individuals.