HOMA-IR Equation:
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The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin resistance from fasting blood glucose and insulin levels.
The calculator uses the HOMA-IR equation:
Where:
Explanation: The equation calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels.
Details: HOMA-IR is crucial for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular diseases.
Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0).
Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest insulin resistance.
Q2: When should I test for HOMA-IR?
A: Testing is recommended when assessing for insulin resistance, metabolic syndrome, or risk for type 2 diabetes.
Q3: Are there limitations to HOMA-IR?
A: HOMA-IR is less accurate in individuals with impaired glucose tolerance or diabetes, and may not reflect postprandial insulin sensitivity.
Q4: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context, typically annually for at-risk individuals.
Q5: Can HOMA-IR be used for diagnosis?
A: While useful for assessment, HOMA-IR should be used alongside other clinical evaluations rather than as a sole diagnostic tool.