1. What is the HOMA-B Index?

The HOMA-B (Homeostatic Model Assessment for Beta Cell Function) index estimates pancreatic beta cell function from fasting insulin and glucose levels. It provides an assessment of insulin secretion capacity and is used in diabetes research and clinical practice.

2. How Does the Calculator Work?

The calculator uses the HOMA-B formula:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL

Explanation: The equation calculates beta cell function as a percentage, with higher values indicating better insulin secretion capacity.

3. Importance of HOMA-B Calculation

Details: HOMA-B assessment is crucial for evaluating insulin secretion capacity, diagnosing insulin resistance patterns, and monitoring beta cell function in diabetes management and research studies.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0) and fasting glucose cannot be exactly 63 mg/dL.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-B value?
A: Normal HOMA-B values typically range from 100-150%, though this can vary based on age, weight, and ethnic background.

Q2: How does HOMA-B differ from HOMA-IR?
A: HOMA-B assesses beta cell function (insulin secretion), while HOMA-IR assesses insulin resistance. Both are calculated from fasting insulin and glucose levels.

Q3: When should HOMA-B be measured?
A: Morning fasting samples are required after an overnight fast of 8-12 hours for accurate results.

Q4: Are there limitations to the HOMA-B model?
A: The model assumes a linear relationship and may be less accurate in extreme glucose levels or in populations with significant insulin resistance.

Q5: Can HOMA-B be used for diabetes diagnosis?
A: HOMA-B is primarily used for research and monitoring purposes rather than standalone diagnosis. Clinical diagnosis should be based on standard glucose tolerance tests and HbA1c measurements.