1. What is the HOMA-B Calculator?

The HOMA-B (Homeostatic Model Assessment for Beta Cell Function) calculator estimates pancreatic beta cell function from fasting insulin and glucose levels. It provides an assessment of insulin secretion capacity in individuals.

2. How Does the Calculator Work?

The calculator uses the HOMA-B formula:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL

Explanation: The formula calculates beta cell function as a percentage of normal, with higher values indicating better insulin secretion capacity.

3. Importance of HOMA-B Calculation

Details: HOMA-B assessment is crucial for evaluating insulin secretion capacity, diagnosing insulin resistance patterns, and monitoring beta cell function in diabetic and pre-diabetic patients.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0). Note that glucose cannot be exactly 63 mg/dL as this would make the denominator zero.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-B value?
A: Normal HOMA-B values typically range from 100% to 180%, indicating normal beta cell function.

Q2: How does HOMA-B relate to diabetes?
A: Lower HOMA-B values indicate impaired beta cell function, which is characteristic of type 2 diabetes progression.

Q3: When should insulin and glucose be measured?
A: Both should be measured after an 8-12 hour fasting period for accurate results.

Q4: Are there limitations to HOMA-B calculation?
A: HOMA-B provides an estimate rather than direct measurement and may be less accurate in certain populations or extreme metabolic conditions.

Q5: Can HOMA-B be used for treatment decisions?
A: While useful for assessment, treatment decisions should be based on comprehensive clinical evaluation rather than HOMA-B alone.