1. What is the HOMA-B Calculation?

The HOMA-B (Homeostatic Model Assessment for Beta Cell Function) calculation estimates pancreatic beta cell function from fasting insulin and glucose levels. It provides an assessment of insulin secretion capacity and beta cell function.

2. How Does the Calculator Work?

The calculator uses the HOMA-B equation:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL

Explanation: The equation calculates beta cell function as a percentage of normal, with higher values indicating better insulin secretion capacity.

3. Importance of HOMA-B Calculation

Details: HOMA-B assessment is crucial for evaluating insulin secretion capacity, diagnosing insulin resistance patterns, and monitoring beta cell function in diabetes management.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Glucose values must be greater than 63 mg/dL for valid calculation.

5. Frequently Asked Questions (FAQ)

Q1: What are normal HOMA-B values?
A: Normal HOMA-B values typically range from 100% to 180%, indicating normal beta cell function.

Q2: When should HOMA-B be measured?
A: Morning fasting sample after an overnight fast is required for accurate measurement.

Q3: What do low HOMA-B values indicate?
A: Low values suggest impaired beta cell function and reduced insulin secretion capacity.

Q4: Are there limitations to this calculation?
A: Less accurate in extremes of glucose levels, during acute illness, or with rapidly changing metabolic conditions.

Q5: How does HOMA-B relate to diabetes diagnosis?
A: HOMA-B helps assess beta cell dysfunction, which is a key component in type 2 diabetes pathophysiology.