Formula Para Calcular HOMA IR

HOMA-IR Equation:

\[ HOMA-IR = \frac{\text{Fasting Insulin} \times \text{Fasting Glucose}}{22.5} \]

HOMA-IR Score:

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1. What is the HOMA-IR Equation?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides a simple way to assess insulin sensitivity from fasting glucose and insulin measurements.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

\[ HOMA-IR = \frac{\text{Fasting Insulin} \times \text{Fasting Glucose}}{22.5} \]

Where:

Fasting Insulin — Measured in micro international units per liter (μU/L)
Fasting Glucose — Measured in millimoles per liter (mmol/L)
22.5 — Normalization constant

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels, with higher values indicating greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is widely used in clinical research and practice to identify insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be valid (greater than 0). For accurate results, measurements should be taken after an overnight fast.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest significant insulin resistance.

Q2: How does HOMA-IR compare to other insulin resistance tests?
A: HOMA-IR is simpler and less expensive than more complex tests like hyperinsulinemic-euglycemic clamps, though it may be less accurate in some populations.

Q3: When should HOMA-IR be measured?
A: Morning fasting samples are essential. Avoid testing after meals, stress, or illness as these can affect results.

Q4: Are there limitations to the HOMA-IR equation?
A: The equation assumes normal liver glucose output and may be less accurate in patients with liver disease or type 1 diabetes.

Q5: Can HOMA-IR be used for diagnosis?
A: While useful for screening and research, HOMA-IR should be interpreted alongside clinical findings and other tests for definitive diagnosis.