1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin sensitivity based on fasting glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in micro international units per milliliter (μU/mL)
• Fasting Glucose — Measured in millimoles per liter (mmol/L)
• 22.5 — Constant derived from normal values

Explanation: The formula calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is crucial for assessing insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular diseases. It helps in early detection and monitoring of insulin sensitivity.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Normal HOMA-IR values are typically below 2.0. Values above 2.0 may indicate insulin resistance.

Q2: How should I prepare for the test?
A: You should fast for 8-12 hours before the blood test to ensure accurate fasting insulin and glucose measurements.

Q3: Can HOMA-IR be used for diagnosis?
A: While HOMA-IR is a useful screening tool, it should not be used alone for diagnosis. Clinical evaluation and other tests are necessary for definitive diagnosis.

Q4: Are there limitations to HOMA-IR?
A: Yes, HOMA-IR may be less accurate in certain populations, such as those with extreme obesity, type 1 diabetes, or pancreatic disorders.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context. It's typically used for initial assessment and periodic monitoring in at-risk individuals.