1. What is HOMA-B?

HOMA-B (Homeostatic Model Assessment for Beta Cell Function) is a mathematical model that estimates beta cell function from fasting insulin and glucose levels. It provides an assessment of pancreatic beta cell function in the fasting state.

2. How Does the Calculator Work?

The calculator uses the HOMA-B formula:

Where:

• Fasting Insulin — Measured in μU/L
• Fasting Glucose — Measured in mmol/L

Explanation: The formula calculates beta cell function as a percentage of normal, with 100% representing normal function.

3. Importance of HOMA-B Calculation

Details: HOMA-B is used in research and clinical practice to assess insulin secretion capacity and beta cell function, particularly in diabetes and metabolic syndrome studies.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be greater than zero, and glucose must be greater than 3.5 mmol/L for valid calculation.

5. Frequently Asked Questions (FAQ)

Q1: What are normal HOMA-B values?
A: Normal HOMA-B values typically range from 80% to 120%, with 100% representing normal beta cell function.

Q2: When should HOMA-B be measured?
A: HOMA-B should be measured after an overnight fast (8-12 hours) for accurate results.

Q3: What does a low HOMA-B value indicate?
A: Low HOMA-B values indicate impaired beta cell function and reduced insulin secretion capacity.

Q4: Are there limitations to HOMA-B?
A: HOMA-B provides an estimate rather than direct measurement and may be less accurate in certain populations or extreme metabolic conditions.

Q5: Can HOMA-B be used for diagnosis?
A: HOMA-B is primarily used for research purposes and should not be used alone for clinical diagnosis without additional tests and clinical evaluation.