1. What Is The HOMA-IR Index?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin sensitivity from fasting glucose and insulin levels.

2. How Does The Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• Fasting Insulin — Measured in μU/mL (microinternational units per milliliter)
• Fasting Glucose — Measured in mmol/L (millimoles per liter)
• 22.5 — Normalization constant

Explanation: The equation calculates insulin resistance based on the product of fasting insulin and glucose levels, normalized by the constant 22.5.

3. Importance Of HOMA-IR Calculation

Details: HOMA-IR is widely used in clinical research and practice to assess insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease risk.

4. Using The Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 2.0 are considered normal, while values above 2.5-3.0 indicate insulin resistance.

Q2: When should insulin and glucose be measured?
A: Both should be measured after an 8-12 hour fast for accurate results.

Q3: Are there limitations to HOMA-IR?
A: Yes, it's less accurate in individuals with impaired beta-cell function and may not reflect postprandial insulin sensitivity.

Q4: Can HOMA-IR be used for diagnosis?
A: It's a screening tool rather than a diagnostic test. Clinical evaluation and other tests are needed for definitive diagnosis.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context, typically as part of metabolic health assessments.