1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin resistance from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• Fasting Insulin — Measured in μU/L (microinternational units per liter)
• Fasting Glucose — Measured in mmol/L (millimoles per liter)
• 22.5 — Normalization constant

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels, with higher values indicating greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is a valuable tool for assessing insulin resistance, which is associated with various metabolic disorders including type 2 diabetes, metabolic syndrome, and cardiovascular diseases.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 2.0 are considered normal, though this may vary by population and laboratory standards.

Q2: When should HOMA-IR be measured?
A: After an overnight fast of 8-12 hours, ideally in the morning before any food or caloric intake.

Q3: Are there limitations to HOMA-IR?
A: While useful for population studies, it may be less accurate for individuals with extreme insulin resistance or beta-cell dysfunction.

Q4: Can HOMA-IR be used for diagnosis?
A: It's primarily used as a screening tool and research measure rather than a definitive diagnostic test.

Q5: How often should HOMA-IR be tested?
A: Frequency depends on individual risk factors and clinical context, typically as part of metabolic health assessments.