HOMA-IR Equation:
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The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) equation estimates insulin resistance using fasting insulin and glucose levels. Higher values indicate greater insulin resistance, which is associated with metabolic disorders including type 2 diabetes.
The calculator uses the HOMA-IR equation:
Where:
Explanation: The equation provides a simple method to assess insulin resistance by quantifying the relationship between fasting insulin and glucose levels.
Details: HOMA-IR is a valuable tool for identifying insulin resistance, which is a key factor in metabolic syndrome, prediabetes, and type 2 diabetes. Early detection allows for lifestyle interventions to prevent disease progression.
Tips: Enter fasting insulin in μU/mL and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.
Q1: What is a normal HOMA-IR value?
A: Typically, values below 2.0 are considered normal, while values above 2.5 suggest insulin resistance. However, reference ranges may vary.
Q2: When should I measure insulin and glucose?
A: Both measurements should be taken after an 8-12 hour overnight fast for accurate results.
Q3: Are there limitations to HOMA-IR?
A: While useful for population studies, HOMA-IR may be less accurate in individuals with impaired beta-cell function or those taking certain medications.
Q4: Can HOMA-IR diagnose diabetes?
A: HOMA-IR indicates insulin resistance but should not be used alone to diagnose diabetes. Oral glucose tolerance tests and HbA1c are preferred for diagnosis.
Q5: How can I improve my HOMA-IR score?
A: Lifestyle modifications including weight loss, regular exercise, and a balanced diet low in refined carbohydrates can improve insulin sensitivity.