1. What is the HOMA-IR Index?

The HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It's calculated from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• Fasting Insulin — Measured in μU/mL (microinternational units per milliliter)
• Fasting Glucose — Measured in mmol/L (millimoles per liter)

Explanation: The equation provides an estimate of insulin resistance, with higher values indicating greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is a valuable tool for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest insulin resistance.

Q2: When should the blood test be performed?
A: After an 8-12 hour fast, ideally in the morning to ensure accurate fasting measurements.

Q3: Are there limitations to HOMA-IR?
A: Yes, it's less accurate in people with impaired glucose tolerance or diabetes and doesn't account for variations in hepatic or peripheral insulin sensitivity.

Q4: Can HOMA-IR be used for diagnosis?
A: It's a screening tool rather than a diagnostic test. Clinical correlation and additional testing are usually needed for diagnosis.

Q5: How often should HOMA-IR be measured?
A: This depends on individual risk factors and should be determined by a healthcare provider based on clinical context.