Home
Back
HOMA-IR Formula:
| From: | To: |
HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin resistance from fasting blood glucose and insulin levels.
The calculator uses the HOMA-IR formula:
Where:
Explanation: The formula calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels. Higher values indicate greater insulin resistance.
Details: HOMA-IR is widely used in research and clinical practice to assess insulin resistance, which is a key factor in metabolic syndrome, type 2 diabetes, and cardiovascular disease risk assessment.
Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be greater than zero for accurate calculation.
Q1: What are normal HOMA-IR values?
A: Normal HOMA-IR values typically range from 1.0 to 1.5. Values above 2.0 indicate insulin resistance, while values above 2.5 suggest significant insulin resistance.
Q2: When should HOMA-IR testing be done?
A: Testing should be performed after an overnight fast (8-12 hours) for accurate results. Avoid testing after meals or strenuous exercise.
Q3: Are there limitations to HOMA-IR?
A: HOMA-IR provides an estimate rather than a direct measurement of insulin resistance. It may be less accurate in certain populations, such as those with type 1 diabetes or advanced liver disease.
Q4: How often should HOMA-IR be measured?
A: The frequency depends on individual risk factors and clinical context. It's typically used for initial assessment and periodic monitoring in at-risk individuals.
Q5: Can HOMA-IR be used for diagnosis?
A: While HOMA-IR is a useful screening tool, diagnosis of insulin resistance should be confirmed with additional clinical assessment and possibly more direct measures of insulin sensitivity.