1. What is the HOMA-IR Index?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin resistance from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in micro international units per milliliter (μU/mL)
• Fasting Glucose — Measured in milligrams per deciliter (mg/dL)
• 405 — Normalization constant

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting glucose and insulin levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is crucial for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be valid (greater than 0). For accurate results, measurements should be taken after an 8-12 hour fast.

5. Frequently Asked Questions (FAQ)

Q1: What are normal HOMA-IR values?
A: Normal HOMA-IR values are typically below 2.0. Values above 2.0 may indicate insulin resistance.

Q2: When should insulin and glucose be measured?
A: Measurements should be taken after an 8-12 hour overnight fast for accurate results.

Q3: Are there limitations to the HOMA-IR calculation?
A: HOMA-IR may be less accurate in certain populations, such as those with type 1 diabetes or advanced liver disease.

Q4: How often should HOMA-IR be calculated?
A: Frequency depends on individual risk factors and clinical context, typically as part of metabolic health assessments.

Q5: Can HOMA-IR be used for diagnosis?
A: While HOMA-IR is a useful screening tool, diagnosis of insulin resistance should be confirmed with additional clinical assessment and tests.