1. What is the HOMA-IR Index?

The HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It's calculated from fasting blood glucose and insulin levels, providing an estimate of insulin sensitivity.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mg/dL

Explanation: The formula estimates insulin resistance by assessing the relationship between fasting glucose and insulin levels. Higher values indicate greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is widely used in research and clinical practice to identify insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mg/dL. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest significant insulin resistance.

Q2: When should HOMA-IR be measured?
A: It should be calculated from fasting blood samples taken after an overnight fast of 8-12 hours.

Q3: Are there limitations to HOMA-IR?
A: Yes, it's less accurate in people with impaired beta-cell function and may not reflect postprandial glucose metabolism.

Q4: Can HOMA-IR be used for diagnosis?
A: While useful for research and screening, it's not typically used as a standalone diagnostic tool for diabetes.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and should be determined by a healthcare provider.