1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin sensitivity based on fasting glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in micro units per milliliter (μU/mL)
• Fasting Glucose — Measured in millimoles per liter (mmol/L)
• 22.5 — Normalization constant

Explanation: The formula calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is widely used in clinical research and practice to identify insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular diseases.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, HOMA-IR values below 2.0 are considered normal, while values above 2.9 may indicate insulin resistance.

Q2: When should I measure fasting insulin and glucose?
A: After an overnight fast of 8-12 hours, preferably in the morning before any food or drink consumption.

Q3: Are there limitations to HOMA-IR?
A: Yes, it may not be as accurate in certain populations such as pregnant women, children, or individuals with extreme insulin levels.

Q4: Can HOMA-IR be used for diagnosis?
A: While useful for screening and research, it should not be used alone for clinical diagnosis without additional tests.

Q5: What units are required for the calculation?
A: Insulin must be in μU/mL and glucose in mmol/L. Conversion may be needed if using different units.