1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function from fasting glucose and insulin measurements.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in μU/L
• Fasting Glucose — Measured in mmol/L
• 22.5 — Normalization constant

Explanation: The equation provides a simple method to estimate insulin resistance based on fasting blood measurements.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is widely used in research and clinical practice to assess insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease risk.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 2.0 are considered normal, though this may vary by population and laboratory standards.

Q2: How should fasting samples be collected?
A: Blood samples should be collected after an 8-12 hour overnight fast for accurate results.

Q3: Are there limitations to HOMA-IR?
A: While useful for population studies, HOMA-IR may be less accurate in individuals with extreme insulin levels or impaired beta-cell function.

Q4: Can HOMA-IR be used for diagnosis?
A: HOMA-IR is primarily a research tool and screening method, not a definitive diagnostic test for insulin resistance.

Q5: What are the units for HOMA-IR calculation?
A: The formula requires insulin in μU/L and glucose in mmol/L. Conversion may be needed if using different units.