1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin sensitivity from fasting glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• Fasting Insulin — Measured in micro international units per liter (μU/L)
• Fasting Glucose — Measured in millimoles per liter (mmol/L)
• 22.5 — Normalization constant

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting insulin and glucose levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is important for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, cardiovascular disease, and other health conditions.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 2.0 are considered normal insulin sensitivity, while values above 2.9 indicate insulin resistance.

Q2: When should HOMA-IR testing be done?
A: Testing should be performed after an overnight fast of 8-12 hours for accurate results.

Q3: Are there limitations to HOMA-IR?
A: HOMA-IR provides an estimate rather than a direct measurement and may be less accurate in certain populations or extreme conditions.

Q4: Can HOMA-IR be used for diagnosis?
A: While useful for screening and research, clinical diagnosis should be based on comprehensive assessment including other tests.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context, typically as part of metabolic health assessment.