Calcular Índice HOMA IR

HOMA-IR Formula:

\[ HOMA-IR = \frac{Fasting\ Insulin\ (\mu U/mL) \times Fasting\ Glucose\ (mmol/L)}{22.5} \]

HOMA-IR Index:

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1. What is the HOMA-IR Index?

The HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It's calculated from fasting blood glucose and insulin levels, providing an estimate of insulin sensitivity.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

\[ HOMA-IR = \frac{Fasting\ Insulin\ (\mu U/mL) \times Fasting\ Glucose\ (mmol/L)}{22.5} \]

Where:

Fasting Insulin — Measured in micro international units per milliliter (μU/mL)
Fasting Glucose — Measured in millimoles per liter (mmol/L)
22.5 — Normalization constant derived from healthy populations

Explanation: The equation estimates insulin resistance by assessing the relationship between fasting glucose and insulin levels. Higher values indicate greater insulin resistance.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is a valuable tool for assessing insulin resistance, which is associated with metabolic syndrome, type 2 diabetes, cardiovascular disease, and other health conditions. It helps in early detection and monitoring of insulin resistance.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mmol/L. Both values must be obtained from a fasting blood sample (typically 8-12 hours fasting). All values must be valid (greater than 0).

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity. Values between 1.0-1.9 suggest early insulin resistance, while values above 2.0 indicate significant insulin resistance.

Q2: Can HOMA-IR diagnose diabetes?
A: HOMA-IR assesses insulin resistance but is not a diagnostic tool for diabetes. Formal glucose tolerance tests and HbA1c measurements are used for diabetes diagnosis.

Q3: Are there limitations to HOMA-IR?
A: Yes, it's less accurate in people with impaired beta-cell function, those on insulin therapy, or with extremely high/low insulin levels. It provides an estimate rather than a precise measurement.

Q4: When should HOMA-IR be measured?
A: It's typically used in research settings and clinical evaluations for metabolic disorders. It may be recommended for individuals with risk factors for insulin resistance.

Q5: How can I improve my HOMA-IR score?
A: Lifestyle modifications including regular exercise, weight management, and a balanced diet low in refined carbohydrates can help improve insulin sensitivity.