1. What is the HOMA-IR Index?

The HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) index is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin resistance from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• Fasting Insulin — Measured in μU/L
• Fasting Glucose — Measured in mmol/L

Explanation: The equation calculates insulin resistance based on the product of fasting insulin and glucose levels, normalized by the constant 22.5.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is important for assessing insulin resistance, which is associated with various metabolic disorders including type 2 diabetes, metabolic syndrome, and cardiovascular diseases.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be valid (greater than 0).

5. Frequently Asked Questions (FAQ)

Q1: What are normal HOMA-IR values?
A: Normal values are typically less than 2.5. Values above this may indicate insulin resistance.

Q2: When should insulin and glucose be measured?
A: Both should be measured after an overnight fast of at least 8 hours for accurate results.

Q3: Are there limitations to the HOMA-IR index?
A: HOMA-IR provides an estimate and may not be as accurate as more complex tests like the hyperinsulinemic-euglycemic clamp.

Q4: Can HOMA-IR be used for diagnosis?
A: While useful for screening and research, clinical diagnosis should be based on comprehensive evaluation including other tests.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context, typically as part of metabolic health assessments.