1. What is the HOMA-IR Index?

The HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It's calculated from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR equation:

Where:

• Fasting Insulin — Measured in μU/mL
• Fasting Glucose — Measured in mmol/L
• 22.5 — Normalization constant

Explanation: The equation estimates insulin resistance based on the product of fasting insulin and glucose levels, normalized by a constant factor.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is a simple and reliable method to assess insulin resistance, which is a key factor in metabolic syndrome, type 2 diabetes, and cardiovascular diseases.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest significant insulin resistance.

Q2: When should the test be performed?
A: After an overnight fast of 8-12 hours, in the morning, to ensure accurate fasting measurements.

Q3: Are there limitations to HOMA-IR?
A: While useful for population studies, it may be less accurate for individuals with extreme insulin resistance or beta-cell dysfunction.

Q4: Can HOMA-IR diagnose diabetes?
A: No, HOMA-IR assesses insulin resistance but is not a diagnostic tool for diabetes. Formal glucose tolerance tests are needed for diagnosis.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context, typically as part of metabolic health assessments.