1. What is the HOMA-B Index?

The HOMA-B (Homeostatic Model Assessment for Beta Cell Function) index estimates pancreatic beta-cell function from fasting insulin and glucose levels. It provides an assessment of insulin secretion capacity.

2. How Does the Calculator Work?

The calculator uses the HOMA-B equation:

Where:

• Fasting Insulin — Measured in μU/L
• Fasting Glucose — Measured in mmol/L

Explanation: The equation calculates beta-cell function based on the relationship between fasting insulin and glucose levels.

3. Importance of HOMA-B Calculation

Details: HOMA-B assessment is crucial for evaluating pancreatic beta-cell function, diagnosing insulin resistance patterns, and monitoring diabetes progression.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be valid positive numbers, and glucose must be greater than 3.5 mmol/L for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What are normal HOMA-B values?
A: Normal HOMA-B values typically range between 100-150%, though this can vary based on population and laboratory standards.

Q2: When should insulin and glucose be measured?
A: Morning fasting samples are required after an 8-12 hour overnight fast for accurate results.

Q3: What does a low HOMA-B value indicate?
A: Low HOMA-B values suggest impaired beta-cell function and reduced insulin secretion capacity.

Q4: Are there limitations to this equation?
A: The equation assumes steady-state conditions and may be less accurate in certain metabolic states or extreme values.

Q5: Can HOMA-B be used for diabetes diagnosis?
A: While HOMA-B provides valuable information about beta-cell function, it should be used alongside other clinical assessments for diabetes diagnosis.