1. What is HOMA-IR?

HOMA-IR (Homeostatic Model Assessment for Insulin Resistance) is a method used to quantify insulin resistance and beta-cell function. It provides an estimate of insulin resistance from fasting blood glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in μU/L (microinternational units per liter)
• Fasting Glucose — Measured in mmol/L (millimoles per liter)
• 22.5 — Normalization constant

Explanation: The equation calculates insulin resistance by assessing the relationship between fasting glucose and insulin levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is valuable for assessing insulin resistance in clinical and research settings, helping identify individuals at risk for type 2 diabetes and metabolic syndrome.

4. Using the Calculator

Tips: Enter fasting insulin in μU/L and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest insulin resistance.

Q2: When should HOMA-IR be measured?
A: After an overnight fast (8-12 hours) for accurate results. Avoid testing after meals or strenuous exercise.

Q3: Are there limitations to HOMA-IR?
A: Yes, it's less accurate in individuals with impaired beta-cell function or those taking medications that affect insulin secretion.

Q4: Can HOMA-IR be used for diagnosis?
A: It's a screening tool rather than a diagnostic test. Clinical correlation and additional tests are usually needed for diagnosis.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and clinical context. Typically monitored annually in at-risk populations.