HOMA-IR Equation:
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The HOMA (Homeostatic Model Assessment) index is a method used to quantify insulin resistance and beta-cell function. The HOMA-IR (Insulin Resistance) score is calculated from fasting insulin and glucose levels.
The calculator uses the HOMA-IR equation:
Where:
Explanation: The equation provides a simple yet effective method to estimate insulin resistance from basic fasting measurements.
Details: HOMA-IR is widely used in clinical research and practice to assess insulin resistance, which is a key factor in metabolic syndrome, type 2 diabetes, and cardiovascular diseases.
Tips: Enter fasting insulin in μU/mL and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.
Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest significant insulin resistance.
Q2: Are there limitations to the HOMA model?
A: Yes, HOMA provides an estimate rather than a direct measurement and may be less accurate in certain populations like those with type 1 diabetes.
Q3: When should the test be performed?
A: After an overnight fast of 8-12 hours, avoiding strenuous exercise before the test.
Q4: Can HOMA-IR be used for diagnosis?
A: While useful for screening and research, it should be used alongside other clinical assessments for diagnosis.
Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and should be determined by healthcare providers.