1. What is the HOMA Index?

The HOMA (Homeostatic Model Assessment) Index is a method used to quantify insulin resistance and beta-cell function. HOMA-IR specifically measures insulin resistance using fasting glucose and insulin levels.

2. How Does the Calculator Work?

The calculator uses the HOMA-IR formula:

Where:

• Fasting Insulin — Measured in micro international units per milliliter (μU/mL)
• Fasting Glucose — Measured in millimoles per liter (mmol/L)
• 22.5 — Normalization constant

Explanation: The formula estimates insulin resistance by assessing the relationship between fasting glucose and insulin levels.

3. Importance of HOMA-IR Calculation

Details: HOMA-IR is widely used in research and clinical practice to identify insulin resistance, which is associated with type 2 diabetes, metabolic syndrome, and cardiovascular disease.

4. Using the Calculator

Tips: Enter fasting insulin in μU/mL and fasting glucose in mmol/L. Both values must be greater than zero for accurate calculation.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal HOMA-IR value?
A: Typically, values below 1.0 indicate normal insulin sensitivity, while values above 2.0 suggest insulin resistance.

Q2: When should the blood test be done?
A: After an overnight fast of 8-12 hours for accurate results.

Q3: Are there limitations to HOMA-IR?
A: Yes, it may not be accurate in certain conditions like type 1 diabetes, liver disease, or when using medications that affect insulin secretion.

Q4: Can HOMA-IR be used for diagnosis?
A: It's a screening tool rather than a diagnostic test. Clinical correlation and additional tests are usually needed for diagnosis.

Q5: How often should HOMA-IR be measured?
A: Frequency depends on individual risk factors and should be determined by a healthcare provider.